Emerging Neurotoxins
Letybo Neurotoxin in Frankfort, IL
Letybo (letibotulinumtoxinA-wlbg) is a modern FDA-approved neurotoxin recently launched in the United States. Here is what Frankfort patients need to know about this new option.
Last reviewed: July 14, 2026·Our editorial standards
Clinical Insight: Express Med Spa Frankfort
“Letybo is one of the newest FDA-approved neuromodulators to enter the U.S. aesthetic market. It provides patients in the Frankfort community access to modern, high-potency wrinkle relaxation backed by extensive international clinical trial data for glabella '11' lines.”
- Stefanie Drozd, MSN, APRN, Founder & Board-Certified Nurse Practitioner

What is Letybo?
Letybo (letibotulinumtoxinA-wlbg) is manufactured by Hugel, Inc. and received U.S. Food and Drug Administration (FDA) approval in early 2024 for the temporary improvement of moderate-to-severe glabellar lines (frown lines between the eyebrows) in adults. While new to the American aesthetic market, Letybo has been a leading neurotoxin in Asia and Europe for years, supported by robust global safety data.
Clinical Efficacy & Patient Experience
In Phase 3 clinical trials (BLESS-1 and BLESS-2), Letybo demonstrated high response rates with significant improvement in frown line severity at 4 weeks post-injection. Clinical trials established that results typically last 3 to 4 months, consistent with major established brands like Botox and Xeomin.
Source: American Academy of Dermatology - Botulinum toxin therapy: Overview · U.S. Food & Drug Administration - Drugs
Why Patients Choose Letybo
As med spas in Frankfort expand their injectable offerings, Letybo offers patients a high-performing alternative with proven consistency. It allows experienced injectors to tailor treatments precisely to each patient's muscle mass and aesthetic preferences.
Availability & Local Med Spa Pricing
Letybo is available at select forward-thinking aesthetic clinics in Frankfort, including Express Med Spa. Pricing is structured competitively against traditional neurotoxins. To learn more about treatment options, view our full Botox & injectable treatment guide.
Interested in trying Letybo for your wrinkle smoothing?
Express Med Spa Frankfort, our featured provider, can answer your questions and check whether Botox is right for you at a complimentary consultation.